I haven’t had time to write up the entire “Grand Unification Theory” yet but I’ll give you a sneak peak. I happened to be doing more research when I stumbled upon something called the Toluene Pathway Map which shows how Toluene is broken down during biodegradation. Notice that Pseudomonas Putida is included in the map. Interestingly at the very bottom of the biodegradation map was something called Acetaldehyde which I immediately recognized from Jill’s post on BTEX. Toluene will eventually break down to Acetaldehyde . As I began to research Acetaldehyde it seemed to be linked to what I call the “Skin Crawling Family Tree”, that is, those that experience skin crawling sensations. Even more revealing the aldehydes were directly linked to some of the exact sensations that we feel, more on that later in this post.
The “Skin Crawling Family Tree”
All of the groups above suffer from Skin Crawling Sensations and the feeling of Bugs Crawling Under the Skin. What if we there was a common link between all of these groups? That is what this post is all about, I believe there is a common link, and that link is Acetaldehyde.
If you have been following my blog then you know how I have connected Morgellons to Toluene. If you haven’t read the previous posts click on the All Posts page and catch up, it should prove well worth your effort. In my Mr. Morgellons meet Mr. Meth, Your Distant Cousin I documented that Toluene is used in Meth production and they experience severe bug crawling sensations known as “Meth Bugs” or “Crank Bugs”. We know that Toluene breaks down into Acetaldehyde.
It turns out Cocaine users can also experience bug crawling sensations. From the article Cocaine and the Destruction of the Rainforests there is a quote
Annually, according to Peruvian forest engineer Marc J. Dourojeanni, coca growers dump 15 million gallons of kerosene, 8 million gallons of sulphuric acid, 1.6 million gallons of acetone, 1.6 million gallons of the solvent toluene, 16,000 tons of lime and 3,200 tons of carbide into the valley’s watershed.
For more on Cocaine and how it’s made see this DOCUMENT. We know that Toluene breaks down into Acetaldehyde.
Acetaldehyde is the main waste product when Candida die-off occurs. For an interesting article see The Candida/Aldehyde detox pathway and the Molybdenum Connection for more information. The damage that Acetaldehyde causes to the body is tremendous and behind many other common diseases. Also, another good article is Candida Albicans and Acetaldehyde Toxin from which you will find this quote.
These effects of acetylaldehyde are multiplied many times over when candida die off occurs
Skin crawling sensations are common compliant for Candida sufferers. Also, this amazing quote:
The primary detoxification mechanism for scavenging unmetabolized acetaldehyde is sulfur-containing antioxidants [see Figure A]. The two most important are cysteine, a conditionally essential amino acid, and glutathione, a cysteine-containing tripeptide (a three-amino-acid polymer) [see Figure B]. Cysteine and glutathione are active against acetaldehyde (and formaldehyde) because they contain a reduced (unoxidized) form of sulfur called a sulfhydryl group, which contains a sulfur atom bonded to a hydrogen atom (abreviated SH).
Sulfhydryl groups interact with aldehydes to render tham incapable of forming cross links. This “mops up” or scavenges any stray acetaldehyde that is not properly metabolized into acetate (acetic acid) [see Figure A]. Although this is a powerful aldehyde detoxification mechanism, it is easily overwhelmed by the relatively large amounts of alcohol that are typically consumed with alcoholic beverages as compared to the amounts of alcohol and acetaldehyde that are produced through normal metabolism. Fortunately, sulfhydryl antioxidants can easily be fortified through dietary supplementation.
In one experiment with rodents [Sprince et al., 1974], a LD-90 dose of acetaldehyde (the dose that would normally kill 90% of the animals) was completely blocked by pretreatment of the animals with cysteine and vitamins B-1 and C. In other words, none of the cysteine-treated animals succumbed to the lethal dose of acetaldehyde! N-Acetylcysteine (NAC) protected almost as well as cysteine.
In another rodent experiment [Busnel & Lehman, 1980], alcohol’s ability to inhibit swimming after the alcohol had been completely metabolized was blocked by vitamin C. What this and the previous study suggests is that the pharmacologic and toxic effect of alcohol are different. The pharmacological effect (i.e., intoxication or drunkenness) is not inhibited by vitamin C or cysteine, but the toxic effect (e.g., the hangover, nervous irritability, swimming difficulty) is inhibited. This suggests that, with alcohol, you can “have your cake and eat it too.”
If that doesn’t sound exactly what we are going through with Morgellons I don’t know what does, notice how sulfur works so well.
Alcoholics going through DT’s
If you do some searching you will see that some alcoholics go through DTs so bad they experience the sensation of bugs crawling under their skin. It is my suggestion that this occurs when the massive Candida colonies they are maintaining go through die off 3 to 5 days after the alcohol flow is stopped. See Living with Alcohol for it’s link to Acetaldehyde.
Like I have stated in previous blog posts many Morgellons patients have found high Toluene levels in their blood work and its metabolites such as Hippuric acid are found as well. Toluene will also biodegrade down the Benzoate path thus our glass crystals also (covered in another post). Much more can be said here. Of course, as this breaks down into the Acetaldehyde path and we suffer skin crawling just as the Candida sufferer does, it’s not the fungus in our case, it’s the Acetaldehyde being biodegraded from the Toluene in our bodies. I believe that Acetaldehyde causes the skin crawling sensation and not the actual fungus.
Formaldehyde (Tiny insects crawling over the eyes and nose?)
Let’s talk about a close cousin of Acetaldehyde and that is Formaldehyde. There is an amazing research paper out there on this, take a look at this quote:
Skin reactions: …chemical can be both irritating and allergy-causing…(EPA). A slight sensation of tiny insects crawling over the eyes, nose and pharynx (formication) is felt at 2-3 ppm. (Zurlo N, via OSH, NZ.) Contact with the vapour or solution causes skin to become white, rough, hard and anaesthetic due to superficial coagulation necrosis. With long exposure, dermatitis and hypersensitivity frequently result. Prolonged exposure may also cause cracking of skin and ulceration, especially around the fingernails.
I wont bother to post all the links but I could find a thousand posts from Morgellons sufferers stating that they are sure they have bugs or worms crawling all over and in their eyes and around there nose, it’s a very, very common symptom. I too have felt that sensation on my eyes, like a bunch of mites crawling across the surface. Depending on what is laying around in our body I believe that Formaldehyde is often times created internally as well as Acetaldehyde.
This is just a very quick write up. I feel strongly that aldehydes such as Acetaldehyde and Formaldehyde are the dominant causes of our symptoms. I’m glossing over a ton of evidence here such as the Putida and other things, I believe Toluene is being created in our bodies and am sure these are causing my symptoms.
Interestingly N-acetylcysteine (NAC) is great for binding to and ridding the body of Acetaldehyde and so is Molybdenum, and Pantothenic Acid and Pantethine. However remember, I am no doctor. Also, cysteine is readily and abundantly found in human hair which is why I believe we suffer hair loss as the body is using all it can to bind to and rid us of the Acetaldehyde and I believe Formaldehyde is created also based on what chemicals we have laying around in our bodies at the time.
I think that all of the above groups in the “Skin Crawling Family Tree” suffer skin crawling due to the aldehydes being created in their bodies. I believe this could easily be proven. Something is creating Toluene in sufficient quantities in the human body to cause the Morgellons condition. We know Ps. Putida can create Toluene from glucose and that many alleviate their symptoms by cutting out most of the sugar from their diet. Is there a link here? There is a scientific paper out there which I will have to purchase to see the full text but I believe it links Acetaldehyde directly to skin crawling sensations in humans, we know it’s close cousin Formaldehyde already has been proven to do so.
Morgellons is an ongoing chemical reaction happening in our bodies with volatile organic compounds (VOC) such as Toluene. This is either being brought on by bioremediation bacteria which can create Toluene or the mere fact that Toluene is has now so thoroughly penetrated our environment. I hope this blog post spurs you on to do some research on Acetaldehyde and see if what I am saying is true. And if you find even more relevant information please post a comment on this thread.