I was forwarded a link to this article by Joe Keleher I found it well worth reading …
American Academy of Neural Therapy and Institute of Neurobiology (Bellevue, WA, USA)
Institute for Neurobiologie (Stuttgart, Germany)
Academy for Balanced NeuroBiology Ltd (London, United Kingdom).
This lecture was presented by Dietrich Klinghardt M.D., Ph.D. at the Jean Piaget Department at the University of Geneva, Switzerland Oct.2002 to physicians and dentists from Europe, Israel, several Arab countries and Asia.
What are Neurotoxins?
Neurotoxins are substances attracted to the mammalian nervous system. They are absorbed by nerve endings and travel inside the neuron to the cell body. On their way they disrupt vital functions of the nerve cell, such as axonal transport of nutrients, mitochondrial respiration and proper DNA transcription. The body is constantly trying to eliminate neurotoxins via the available exit routes: the liver, kidney, skin and exhaled air. Detox mechanisms include acetylation, sulfation, glucuronidation, oxidation and others. Often the host is triggered to produce neurotoxins (which are damaging to their own tissues) by the invading microbes through molecular trickery.
The liver is most important in the toxin elimination process. Here most elimination products are expelled with the bile into the small intestine and should leave the body via the digestive tract. However, because of the lipophilic/neurotropic nature of the neurotoxins, most are reabsorbed by the abundant nerve endings of the enteric nervous system (ENS) in the intestinal wall. The ENS has more neurons than the spinal chord.
From the moment of mucosal uptake the toxins can potentially take four different paths:
- Neuronal uptake and via axonal transport to the spinal chord (sympathetic neurons) or brainstem (parasympathetics) from here back to the brain.
- Venous uptake and via the portal vein back to the liver
- Lymphatic uptake and via the thoracic duct to the subclavian vein
- Uptake by bowel bacteria and tissues of the intestinal tract.
Here is an incomplete list of common neurotoxins in order of importance:
(i) Heavy metals: such as mercury, lead, cadmium and aluminum.
(ii) Biotoxins: such as tetanus toxin, botulinum toxin (botox), ascaridin (from intestinal parasites), unspecified toxins from streptococci, staphylococci, lyme disease, clamydia, tuberculosis, fungal toxins and toxins produced by viruses. Biotoxins are minute molecules (200-1000 kilodaltons) containing nitrogen and sulfur. They belong to a group of chemical messengers which microorganisms use to control the host’s immune system, host behavior and the host’s eating habits.
(iii) Xenobiotics (man-made environmental toxins): such as dioxin, phthalates, formaldehyde, insecticides, wood preservatives, PCBs etc.
(iv) Food Preservatives, excitotoxins and cosmetics: such as aspartame (diet sweeteners) food colorings, fluoride, methyl-and propyl-paraben, etc.
I have found that mercury in its different chemical forms has a synergistic amplifying effect with all other neurotoxins. When mercury is removed, the body starts to more effectively eliminate all other neurotoxins, even if they are not addressed.
The full article can be found HERE …, quite a weighty read but very interesting. Personally, I wouldn’t go on a massive Detox program without a trained doctor working with me. But this is a good article from an education standpoint, there are some annoying formatting issues in the article however.